C16 Sphingomyelin-d9 is intended for use as an internal standard for the quantification of C16 sphingomyelin (Item No. 10007946) by GC- or LC-MS. C16 Sphingomyelin is a naturally occurring sphingolipid.1,2,3 Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease.1,2 Plasma levels of C16 sphingomyelin are decreased in patients with prostate cancer.3 Model membranes containing C16 sphingomyelin, 1-palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC; Item No. 15102), and cholesterol (Item No. 9003100) have been used in the study of lipid raft dynamics and membrane organization.4,5WARNING This product is not for human or veterinary use.